Keto Creamy Tuscan Salmon Skillet

This keto creamy Tuscan salmon skillet features tender seared salmon in a rich, cheesy sauce with spinach, roasted red peppers, and herbs. A quick and flavorful low-carb dinner idea.

If you’re anything like me, you’re always looking for easy ways to make dinner feel a little more special without spending hours in the kitchen. That’s exactly why I love this keto creamy Tuscan salmon skillet—it’s packed with flavor, uses simple ingredients, and comes together in just one pan. It’s perfect for busy weeknights when I want something comforting and delicious but don’t feel like doing a ton of cleanup afterward.

Salmon is one of those proteins I always try to keep on hand because it’s healthy, quick to cook, and so versatile. I’ve made it a hundred different ways, but this creamy Tuscan version has quickly become a favorite in my house. The combination of garlic, spinach, roasted red peppers, and parmesan cheese creates a rich sauce that tastes like something from a restaurant, without all the carbs or effort.

I first made this on a night when I didn’t have a dinner plan and just threw together what I had in the fridge—and I was shocked at how good it turned out. Now it’s in regular rotation, and even my husband, who isn’t always a fan of “healthy” meals, goes back for seconds. If you’re following a keto or low-carb lifestyle—or just want a seriously tasty salmon dinner—this recipe is definitely one to try.

Items Needed

Here’s what you’ll need to make keto creamy Tuscan salmon skillet:

• Salmon fillets – A rich, tender protein source that’s packed with healthy fats and cooks quickly.
• Olive oil – Used for searing the salmon and adding heart-healthy fat and flavor.
• Salt and pepper – Essential for enhancing the natural flavors of the dish.
• Butter – Adds depth, richness, and helps build the base of the creamy sauce.
• Onion – Provides a savory, slightly sweet flavor that forms the foundation of the sauce.
• Tomato paste – Concentrated tomato flavor that adds a tangy richness and color to the sauce.
• Roasted red peppers – Adds a smoky-sweet element and extra texture to the creamy base.
• Garlic – Delivers a punch of savory, aromatic flavor that complements the salmon and sauce.
• Heavy whipping cream – Creates the creamy, luxurious texture that defines the dish.
• Fresh spinach – Adds nutrients, color, and a light, earthy flavor that balances the richness.
• Parmesan cheese – Brings a salty, umami depth and helps thicken the sauce.
• Basil – Adds a hint of sweetness and a herby note that ties the flavors together.

Ways To Customize

Here are some easy ways to customize this keto creamy Tuscan salmon skillet recipe:

• Swap the protein – Use chicken, shrimp, or even tofu instead of salmon for a different twist.
• Add heat – Mix in a pinch of red pepper flakes or a dash of hot sauce for a spicy kick.
• Use different greens – Replace spinach with kale or arugula for a different texture and flavor.
• Try sun-dried tomatoes – Swap the roasted red peppers for chopped sun-dried tomatoes for a tangier, more intense flavor.
• Make it dairy-free – Use coconut cream and a dairy-free parmesan alternative for a lactose-free version.
• Add mushrooms – Sauté sliced mushrooms with the onions for extra umami and heartiness.
• Change up the herbs – Use Italian seasoning, thyme, or oregano instead of basil for a different herby note.
• Serve it differently – Spoon the salmon and sauce over cauliflower rice, zoodles, or mashed cauliflower to make it a full meal.

How To Make It

Heat the olive oil in a skillet over medium-high heat, and season the salmon with salt and pepper to taste.

Storage

To store leftover keto creamy Tuscan salmon skillet, let it cool completely, then transfer it to an airtight container and refrigerate for up to 3 days. When you’re ready to reheat, gently warm it in a skillet over low heat, adding a splash of cream or water to loosen the sauce if needed. Avoid using high heat or the microwave for too long, as it can dry out the salmon—low and slow is best to keep the fish tender and the sauce creamy.

Helpful Hints

Here are more helpful hints for making this recipe:

1. Use a non-stick or well-seasoned skillet to avoid the salmon sticking and breaking apart.
2. Don’t overcrowd the pan when searing—cook the salmon in batches if needed for an even sear.
3. Let the salmon rest for a few minutes after searing to keep it juicy when added back to the sauce.
4. Chop ingredients ahead of time to keep things moving smoothly once you start cooking.
5. Simmer the sauce gently to prevent the cream from curdling or separating.
6. Taste and adjust the seasoning before serving to make sure the flavors are balanced.
7. Grate your own Parmesan for a smoother melt and richer flavor.

Serving Suggestions

This keto creamy Tuscan salmon skillet is rich and flavorful on its own, but pairing it with the right sides can take it to the next level. For a fully low-carb meal, try serving it over cauliflower rice, zucchini noodles, or mashed cauliflower. These options soak up the creamy sauce beautifully and keep everything keto-friendly without feeling like you’re missing out on a classic comfort meal.

If you’re not strictly low-carb or cooking for mixed eaters, you can serve it with rice, pasta, or even crusty bread to mop up all that delicious sauce. I’ve served it over angel hair pasta for guests before, and it was a big hit. The sauce clings to the noodles really well, and it turns the skillet into a hearty, restaurant-style dish that feels fancy but is super easy to make. And if you love salmon dishes, be sure to check out my Salmon with Creamy Dill Sauce for a fresh and tangy alternative that’s just as easy to make.

For something lighter on the side, a crisp green salad or steamed veggies like broccoli or asparagus are great choices. They add freshness and a bit of crunch to balance out the richness of the sauce. I also recommend pairing this with my Keto Collard Green Salad with Chicken—just skip the chicken if you’re serving it as a side. The tangy dressing and hearty greens are a perfect contrast to the creamy salmon and make for a well-rounded, satisfying meal.

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